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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T38279 | C2-8 | C2-8 | |
C2-8 is an inhibitor of polyglutamine (polyQ) aggregation (IC50s = 25 and 0.05 μM for recombinant HDQ51 and in PC12 cells, respectively). It also inhibits polyQ aggregation in organotypic hippocampal slice cultures isola... | |||
T17916 | Pomalidomide-PEG4-C2-NH2 | Cereblon Ligand-Linker Conjugates 8,E3 Ligase Ligand-Linker Conjugates 22 | Others , Ligand for E3 Ligase |
Pomalidomide-PEG4-C2-NH2 (E3 Ligase Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide-based cereblon ligand and 4-unit PEG linker. | |||
T15961 | Mal-amido-PEG8-C2-acid | Others | |
Mal-amido-PEG8-C2-acid (US2018339985, example 142) is a noncleavable linker for antibody-drug conjugates (ADCs) [1]. | |||
T14892 | Cbz-NH-PEG8-C2-acid | Others | |
Cbz-NH-PEG8-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst... | |||
T17882 | Pomalidomide-PEG3-C2-NH2 (TFA) | Cereblon Ligand-Linker Conjugates 5 (TFA),E3 ligase Ligand-Linker Conjugates 30 (TFA),Pomalidomide-PEG3-C2-NH2 (TFA) (2093416-31-8 free base) | Others |
Pomalidomide-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. |